Adrenal Fatigue: What is it really?

Adrenal Fatigue: What Is It Really?

Do you feel exhausted all the time? Struggle to wake up, brain fog, 3 PM crashes, no energy? Blame "adrenal fatigue" – your glands are "burned out" from too much stress. It is slightly more complicated, more interesting—and more hopeful.

Quick fact: Acute stress shoots cortisol sky-high. Chronic? Not gland burnout, but hormonal resisitance. If that sounds familiar it should, think of this as type II diabetes for your adrenals.

The Explanation

What really happens under stress?

Your adrenal glands sit on top of your kidneys and make cortisol, your main stress hormone.

  • Acute stress (When stress hits fast like a scare or a big deadline) : Cortisol surges via brain signals; this helps you stay alert and focused.

  • Chronic stress (The system starts to wear down): Cortisol starts high, but as time and stress continue it dips. Low cortisol is the result, not because your glands are dead, but because your brain stops listening properly. Production slows because of hormonal resistance not gland death.

  • Low cortisol + low DHEA: Common in exhaustion. DHEA ratio crashes (your stress shield vanishes). Brain signals stay normal resistance sets in.

What's really happening? Chronic stress tweaks brain receptors, slowing signals to the adrenals. It’s a bit like Type 2 diabetes, but instead of insulin resistance, you develop cortisol resistance. Your brain gets “numb” to its own stress signals.

The result?

  • Low energy, poor sleep, mood swings, and slower recovery from stress.

Why Cortisol and DHEA Matter

Cortisol works like your “gas pedal.”
DHEA (another adrenal hormone) is your “brake.” It protects your body from stress damage.

When you’re under chronic stress, DHEA drops too. That means your stress shield is gone—leaving you tired, anxious, and inflamed.

This pattern is called HPA-axis dysfunction (for Hypothalamus-Pituitary-Adrenal), its is not adrenal failure. It’s your brain, not your glands, that needs a reset.

Meet Cortisol Type 2 – Your "Stress Diabetes"

Just like Type 2 diabetes:

  • Start: Resistance → high levels (insulin or cortisol).

  • Crash: System overload → low levels.

  • Fixable: Lifestyle wins.

Entirely reversible!

Fix It Now

1. Calm the stress response.
Practice breathing, meditation, or slow walks outdoors. Small breaks make a big difference.

2. Sleep like it matters.
Aim for 7–9 hours. A dark, cool room helps your brain reset cortisol patterns.

3. Eat to support your adrenals.
Balance protein, healthy fats, and complex carbs. Avoid too much caffeine or sugar, which spike stress hormones.

4. Add adaptogens.
Herbs like ashwagandha, rhodiola, and holy basil can help balance cortisol and energy—ask your provider first.

5. Test, don’t guess.
A saliva cortisol curve not a blood test can show how your hormones shift through the day.

The Takeaway

“Adrenal fatigue” isn’t your glands giving up—it’s your stress system out of balance.
When you understand it, you can fix it.
Call it what it is: Stress-Induced Cortisol Crash.
And yes—it’s reversible.

References

  1. Adrenal fatigue. BMC Endocr Disord. 2016.

  2. Savic I, et al. HPA dysregulation model. eLife. 2020.

  3. Dutheil F, et al. DHEA meta-analysis. Front Psychiatry. 2021.

  4. Lennartsson AK, et al. Front Endocrinol. 2023.

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